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Catalog No: ARP48316_P050
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ARP48316_P050
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Datasheets/ManualsPrintable datasheet for anti-PHB2 (ARP48316_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human PHB2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: KLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
Concentration0.5 mg/ml
Blocking PeptideFor anti-PHB2 (ARP48316_P050) antibody is Catalog # AAP48316 (Previous Catalog # AAPY01686)
Sample Type Confirmation

PHB2 is supported by BioGPS gene expression data to be expressed in HepG2

ReferenceRoss,J.A., (2008) J. Biol. Chem. 283 (8), 4699-4713
Gene SymbolPHB2
Gene Full NameProhibitin 2
Alias SymbolsBAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141
NCBI Gene Id11331
Protein NameProhibitin-2
Description of TargetPHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
Uniprot IDQ99623
Protein Accession #NP_009204
Nucleotide Accession #NM_007273
Protein Size (# AA)299
Molecular Weight33kDa
Protein InteractionsHUWE1; IGF1R; HDAC1; ESR1; KIAA1244; NCOR1; SUMO2; STAU1; UBC; MDM2; ASB14; ASB17; SUZ12; EED; RNF2; UPF2; ADRB2; CDK2; env; VCAM1; TEAD3; ITGA4; ILF3; FN1; ATF2; C1QBP; AFP; UBL4A; EPAS1; FMNL1; PAXIP1; MDC1; MYOD1; MEF2A; FHL2; ECT2; BRCA1; AKT1; Htt; U
  1. What is the species homology for "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit".

  2. How long will it take to receive "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PHB2 Antibody - C-terminal region (ARP48316_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    This target may also be called "BAP, REA, p22, hBAP, Bap37, BCAP37, PNAS-141" in publications.

  5. What is the shipping cost for "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "33kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PHB2 Antibody - C-terminal region (ARP48316_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PHB2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PHB2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PHB2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PHB2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PHB2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PHB2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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