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RELA Antibody (Phospho-Ser311) (OASG05002)

100 uL
$215.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, IF
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-109 from Santa Cruz Biotechnology.
Immunogen:
Synthesized peptide derived from human NFKappaB-p65 around the phosphorylation site of S311. Location: 250-330aa.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-RELA (OASG05002) antibody
Target Post-Translational Modification:
Phospho-Ser311
Specificity:
Phospho-NFKappaB-p65 (S311) Polyclonal Antibody detects endogenous levels of NFKappaB-p65 protein only when phosphorylated at S311.
Application Info:
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000;
Gene Symbol:
RELA
Official Gene Full Name:
v-rel avian reticuloendotheliosis viral oncogene homolog A
Alias Symbols:
RELA, NFKB3, Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
NCBI Gene Id:
5970; 19697;
Description of Target:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Swissprot Id:
Q04206, Q04207
Molecular Weight:
65 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RELA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RELA.

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