Size:100 ug
$315.00
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SKU
OACA02434
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RELA Antibody (OACA02434)

Catalog#: OACA02434
Domestic: within 1-2 weeks delivery | International: 1-2 weeks
More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application IHC, CHIP
Reconstitution and Storage Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item This antibody may replace item sc-109 from Santa Cruz Biotechnology.
Immunogen Recombinant human Transcription factor p65 protein
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence Human
Datasheets/Manuals Printable datasheet for anti-RELA (OACA02434) antibody
Specificity Human
Formulation Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference [1] Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. Saccani S., Marazzi I., Beg A.A., Natoli G.J. Exp. Med. 200:107-113 (2004).
[2] COMMD proteins, a novel family of structural and functional homologs of MURR1. Burstein E., Hoberg J.E., Wilkinson A.S., Rumble J.M., Csomos R.A., Komarck C.M., Maine G.N., Wilkinson J.C., Mayo M.W., Duckett C.S.J. Biol. Chem. 280:22222-22232 (2005).
[3] Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon. Mattioli I., Geng H., Sebald A., Hodel M., Bucher C., Kracht M., Schmitz M.L. J. Biol. Chem. 281:6175-6183 (2006).
Gene Symbol RELA
Official Gene Full Name v-rel avian reticuloendotheliosis viral oncogene homolog A
Alias Symbols p65, NFKB3
NCBI Gene Id 5970
Protein Name transcription factor p65
Description of Target NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Swissprot Id Q04206
Protein Accession # NP_001138610.1
Nucleotide Accession # NM_001145138.1
Protein Size (# AA) 551
Molecular Weight 60 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RELA.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RELA.
  1. What is the species homology for "RELA Antibody (OACA02434)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "RELA Antibody (OACA02434)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "RELA Antibody (OACA02434)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RELA Antibody (OACA02434)"?

    This target may also be called "p65, NFKB3" in publications.

  5. What is the shipping cost for "RELA Antibody (OACA02434)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RELA Antibody (OACA02434)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RELA Antibody (OACA02434)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RELA Antibody (OACA02434)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RELA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RELA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RELA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RELA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RELA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RELA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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