Search Antibody, Protein, and ELISA Kit Solutions

RELA Antibody (OACA02434)

100 ug
$315.00
In Stock
Request Bulk Order Quote

Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item:
This antibody may replace item sc-109 from Santa Cruz Biotechnology.
Immunogen:
Recombinant human Transcription factor p65 protein
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human
Datasheets/Manuals:
Printable datasheet for anti-RELA (OACA02434) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference:
[1] Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. Saccani S., Marazzi I., Beg A.A., Natoli G.J. Exp. Med. 200:107-113 (2004).
[2] COMMD proteins, a novel family of structural and functional homologs of MURR1. Burstein E., Hoberg J.E., Wilkinson A.S., Rumble J.M., Csomos R.A., Komarck C.M., Maine G.N., Wilkinson J.C., Mayo M.W., Duckett C.S.J. Biol. Chem. 280:22222-22232 (2005).
[3] Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon. Mattioli I., Geng H., Sebald A., Hodel M., Bucher C., Kracht M., Schmitz M.L. J. Biol. Chem. 281:6175-6183 (2006).
Gene Symbol:
RELA
Official Gene Full Name:
v-rel avian reticuloendotheliosis viral oncogene homolog A
Alias Symbols:
p65, NFKB3
NCBI Gene Id:
5970
Protein Name:
transcription factor p65
Description of Target:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Swissprot Id:
Q04206
Protein Accession #:
NP_001138610.1
Nucleotide Accession #:
NM_001145138.1
Protein Size (# AA):
551
Molecular Weight:
60 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RELA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RELA.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...