Catalog No: OPAN06663
Price: $349.00
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Datasheets/ManualsPrintable datasheet for Active Recombinant SARS-CoV-2 Spike S1 Protein (OPAN06663)
Product Info
Tested Species Reactivity2019-nCoV
Predicted Species ReactivitySARS-CoV-2 / COVID-19 Virus|Severe acute respiratory syndrome coronavirus 2
Product FormatLyophilized from a 0.22 um filtered solution of PBS, pH 7.4
Additional InformationDescription: The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates thisinteraction.The S protein plays key parts in the induction of neutralizing-antibody and T-cellresponses, as well as protective immunity.
::Endotoxin Level: < 0.1 EU/ug of the protein by LAL method.
Reconstitution and StorageReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Store the lyophilized protein at -20C to -80C for long term. After reconstitution, the protein solution is stable at -20 C for 3 months, at 2-8 C for up to 1 week. Avoid repeated freeze/thaw cycles.
Purity>95% by SDS-PAGE.
Biological ActivityMeasured by its binding ability in a functional ELISA. Immobilized nCoV-S1 at 2 g/mL (100 L/well) can bind Recombinant Human ACE2 with a linear range of 0.06-0.3ug/mL.
Protein SequenceVal11-Arg682 of 2019-ncov Spike S1 (Accession #YP_009724390.1) fused with an Fc, 6 x His tag at the C-terminus.
SourceHEK293 Cells
TagFc, 6 x His tag at the C-terminus
Gene SymbolS
Gene Full Namesurface glycoprotein
Alias SymbolsGU280_gp02;spike glycoprotein;surface glycoprotein.
NCBI Gene Id43740568
Protein Namesurface glycoprotein
Protein Accession #YP_009724390.1
Protein Size (# AA)Active|Recombinant
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