Recombinant Human sIL-6Ralpha Protein (OPTA00891)

Catalog No: OPTA00891

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Mouse, Rat
• Product Format: Lyophilized
• Application: CA
  Bioactivity: The ability to increase the IL-6 induced growth inhibition of murine M1 cells is measured. The expected ED50 for this effect, in the presence of 20 ng/ml recombinant human IL-6, is between <= 5.0 ng/ml.
  Endotoxin Level: Endotoxin level is <0.1 ng/ug of protein (<1 EU/ug).
• Reconstitution and Storage: -20C
• Purity: 98%
• Protein Sequence: LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH WVLRKPAAGS HPSRWAGMGR RLLLRSVQLH DSGNYSCYRA GRPAGTVHLL VDVPPEEPQL SCFRKSPLSN VVCEWGPRST PSLTTKAVLL VRKFQNSPAE DFQEPCQYSQ ESQKFSCQLA VPEGDSSFYI VSMCVASSVG SKFSKTQTFQ GCGILQPDPP ANITVTAVAR NPRWLSVTWQ DPHSWNSSFY RL
• Source: HEK293 cells
• Reference:

  Boulanger MJ, Chow DC, Brevnova EE and Garcia KC. 2003. Science. 300(5628): 2101-2014.

  Kishimoto T, Akira S and Taga T. 1992. Int J Immunopharmacol. 14(3): 431-438.

Target Info

• Alias Symbols: soluble IL-6 receptor alpha, B cell stimulatory factor-2, CD126, IL-6R 1, membrane glycoprotein 80
• Molecular Weight: 37.6 kDa