Catalog No: ARP40431_P050
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ARP40431_P050
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RDBP Antibody - N-terminal region (ARP40431_P050)

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Datasheets/ManualsPrintable datasheet for anti-NELFE (ARP40431_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Yeast
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human RDBP
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%
Peptide SequenceSynthetic peptide located within the following region: LVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLS
Concentration0.5 mg/ml
Blocking PeptideFor anti-NELFE (ARP40431_P050) antibody is Catalog # AAP40431 (Previous Catalog # AAPS03008)
ReferenceRao,J.N., (2008) Biochemistry 47 (12), 3756-3761
Publications

Schulz, M. et al. Quantitative phosphoproteomic analysis of early alterations in protein phosphorylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Proteome Res. 12, 866-82 (2013). 23298284

Gene SymbolNELFE
Gene Full NameRD RNA binding protein
Alias SymbolsRD, RDP, RDBP, D6S45, NELF-E
NCBI Gene Id7936
Protein NameNegative elongation factor E
Description of TargetRDBP is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D).The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP18615
Protein Accession #NP_002895
Nucleotide Accession #NM_002904
Protein Size (# AA)380
Molecular Weight43kDa
Protein InteractionsCCDC57; MTUS2; TRIM27; UBC; SRPK2; SRPK1; LMNA; POLR2C; SUMO1; NELFCD; NELFB; SF3B1; NELFA; TMEM141; RPAP2; WDR48; VAMP3; NCOR1; NELFE; POLR2A; CACTIN;
  1. What is the species homology for "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Yeast".

  2. How long will it take to receive "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RDBP Antibody - N-terminal region (ARP40431_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    This target may also be called "RD, RDP, RDBP, D6S45, NELF-E" in publications.

  5. What is the shipping cost for "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "43kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RDBP Antibody - N-terminal region (ARP40431_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NELFE"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NELFE"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NELFE"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NELFE"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NELFE"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NELFE"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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