Size:400ul
$329.00
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SKU
OAAB12433
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RCOR1 Antibody - N-terminal region (OAAB12433)

Catalog#: OAAB12433
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human, Mouse
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality Polyclonal
Isotype Ig
Host Rabbit
Application WB
Additional Information Precautions: RCOR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
:: Function: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation
:: Cellular Location: Nucleus. Note=Upon infection by HSV-1, it is partially translocated into the cytoplasm in an HSV-1-dependent manner
Tissue Location: Ubiquitously expressed.
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Immunogen This RCOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the N-terminal region of human RCOR1.
Predicted Homology Based on Immunogen Sequence Human; Mouse
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals Printable datasheet for OAAB12433
Sample Type Confirmation

RCOR1 is strongly supported by BioGPS gene expression data to be expressed in ZR75-1

Application Info WB: 1:2000
WB: 1:1000
Gene Symbol RCOR1
Alias Symbols RCOR1, KIAA0071, RCOR, REST corepressor 1, Protein CoREST
NCBI Gene Id 23186
Protein Name REST corepressor 1
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Swissprot Id Q9UKL0
Protein Accession # NP_055971.2
Molecular Weight 53028 Da
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RCOR1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RCOR1.
  1. What is the species homology for "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "RCOR1 Antibody - N-terminal region (OAAB12433)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    This target may also be called "RCOR1, KIAA0071, RCOR, REST corepressor 1, Protein CoREST" in publications.

  5. What is the shipping cost for "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "53028 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RCOR1 Antibody - N-terminal region (OAAB12433)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RCOR1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RCOR1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RCOR1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RCOR1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RCOR1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RCOR1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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