- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for anti-RCHY1 (OAEC04583) antibody |
---|
Predicted Species Reactivity | Human, Rat |
---|---|
Product Format | Ascitic fluid containing 0.03% sodium azide |
Clonality | Monoclonal |
Clone | 1H10 |
Isotype | IgG1 |
Host | Mouse |
Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
Immunogen | Purified recombinant fragment of human Pirh2 expressed in EColi. |
Concentration | 1 mg/ml |
Application Info | WB: 1/500 - 1/2000 IHC: 1/200 - 1/1000 IF: 1/200-1/1000 FC1/200-1/400 ELISA: 1/10000 |
Gene Symbol | RCHY1 |
---|---|
Gene Full Name | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
Alias Symbols | ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996 |
NCBI Gene Id | 25898 |
Description of Target | Pirh 2 (P53 induced RING-H2 protein), also known as RCHY1, it forms dimers through its N- and C-terminus in cells. The Pirh2 has ubiquitin-protein ligase activity and it binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. The Pirh2 is oncogenic because loss of p53 function contributes directly to malignant tumor development. Pirh2 expression decreases the level of p53, and a decrease of endogenous Pirh2 expression increases p53 levels. Pirh2 is therefore considered, together with MDM2, to act as a negative regulator of p53 function. |
Uniprot ID | Q96PM5 |
Molecular Weight | 30 kDa; 60 kDa (homodimer) |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "RCHY1 Antibody (OAEC04583)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Rat".
-
How long will it take to receive "RCHY1 Antibody (OAEC04583)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
-
What buffer format is "RCHY1 Antibody (OAEC04583)" provided in?
This item is provided in "Ascitic fluid containing 0.03% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RCHY1 Antibody (OAEC04583)"?
This target may also be called "ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996" in publications.
-
What is the shipping cost for "RCHY1 Antibody (OAEC04583)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "RCHY1 Antibody (OAEC04583)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "RCHY1 Antibody (OAEC04583)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "30 kDa; 60 kDa (homodimer)".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RCHY1 Antibody (OAEC04583)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "RCHY1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "RCHY1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "RCHY1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "RCHY1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "RCHY1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "RCHY1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.