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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for RBPJ Antibody (OACA09458) (OACA09458) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Recombining binding protein suppressor of hairless protein (243-485AA) |
Purification | Protein G Purified |
Preservative | 0.03% Proclin 300 |
Formulation | 50% Glycerol, 0.01M PBS, PH 7.4 |
Purity | >95% |
Gene Symbol | RBPJ |
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Gene Full Name | recombination signal binding protein for immunoglobulin kappa J region |
Alias Symbols | AOS3;CBF1;CBF-1;csl;H-2K binding factor-2;IGKJRB;IGKJRB1;immunoglobulin kappa J region recombination signal binding protein 1;J kappa-recombination signal-binding protein;KBF2;RBP-J;RBP-J kappa;RBPJK;RBP-JK;RBPSUH;recombining binding protein suppressor of hairless;renal carcinoma antigen NY-REN-30;SUH;suppressor of hairless homolog. |
NCBI Gene Id | 3516 |
Protein Name | Recombining binding protein suppressor of hairless |
Description of Target | Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA (PubMed:21991380). Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (PubMed:23303788). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by repressing transcription of NADPH oxidase subunits (By similarity). |
Uniprot ID | Q06330 |
Protein Accession # | NP_005340 |
Nucleotide Accession # | NM_005349 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "RBPJ Antibody (OACA09458)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "RBPJ Antibody (OACA09458)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "RBPJ Antibody (OACA09458)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RBPJ Antibody (OACA09458)"?
This target may also be called "AOS3;CBF1;CBF-1;csl;H-2K binding factor-2;IGKJRB;IGKJRB1;immunoglobulin kappa J region recombination signal binding protein 1;J kappa-recombination signal-binding protein;KBF2;RBP-J;RBP-J kappa;RBPJK;RBP-JK;RBPSUH;recombining binding protein suppressor of hairless;renal carcinoma antigen NY-REN-30;SUH;suppressor of hairless homolog." in publications.
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What is the shipping cost for "RBPJ Antibody (OACA09458)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "RBPJ Antibody (OACA09458)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "RBPJ Antibody (OACA09458)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RBPJ Antibody (OACA09458)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RBPJ"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RBPJ"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RBPJ"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RBPJ"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RBPJ"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RBPJ"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.