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Catalog No: OACA09954
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SKU
OACA09954
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Datasheets/ManualsPrintable datasheet for RBM4 Antibody (OACA09954) (OACA09954)
Product Info
Predicted Species ReactivityHuman|Mouse
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human RNA-binding protein 4 protein (121-205AA)
PurificationProtein G Purified
Preservative0.03% Proclin 300
Formulation50% Glycerol, 0.01M PBS, PH 7.4
Purity>95%
Gene SymbolRBM4
Gene Full NameRNA binding motif protein 4
Alias SymbolsLARK;lark homolog;RBM4A;RNA-binding motif protein 4;RNA-binding motif protein 4a;RNA-binding protein 4;transcriptional coactivator CoAZ;ZCCHC21;ZCRB3A;zinc finger CCHC-type and RNA binding motif 3A.
NCBI Gene Id5936
Protein NameRNA-binding protein 4
Description of TargetRNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro.
Uniprot IDQ9BWF3
Protein Accession #NP_001185772
Nucleotide Accession #NM_001198843
  1. What is the species homology for "RBM4 Antibody (OACA09954)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".

  2. How long will it take to receive "RBM4 Antibody (OACA09954)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "RBM4 Antibody (OACA09954)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RBM4 Antibody (OACA09954)"?

    This target may also be called "LARK;lark homolog;RBM4A;RNA-binding motif protein 4;RNA-binding motif protein 4a;RNA-binding protein 4;transcriptional coactivator CoAZ;ZCCHC21;ZCRB3A;zinc finger CCHC-type and RNA binding motif 3A." in publications.

  5. What is the shipping cost for "RBM4 Antibody (OACA09954)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RBM4 Antibody (OACA09954)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RBM4 Antibody (OACA09954)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RBM4 Antibody (OACA09954)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RBM4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RBM4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RBM4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RBM4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RBM4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RBM4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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