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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-RBL2 (OAAB19758) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50% |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB, ICC |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Application Info | WB: 1:1000 |
| Reference | Li Y.,et al.Genes Dev. 7:2366-2377(1993). Hannon G.J.,et al.Genes Dev. 7:2378-2391(1993). Mayol X.,et al.Oncogene 8:2561-2566(1993). Baldi A.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:4629-4632(1996). Canhoto A.J.,et al.Oncogene 19:5116-5122(2000). |
| Gene Symbol | RBL2 |
|---|---|
| Alias Symbols | Rb2, P130 |
| NCBI Gene Id | 5934 |
| Description of Target | Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor. |
| Uniprot ID | Q08999 |
| Molecular Weight | 128 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "RBL2 Antibody (OAAB19758)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "RBL2 Antibody (OAAB19758)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "RBL2 Antibody (OAAB19758)" provided in?
This item is provided in "0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RBL2 Antibody (OAAB19758)"?
This target may also be called "Rb2, P130" in publications.
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What is the shipping cost for "RBL2 Antibody (OAAB19758)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "RBL2 Antibody (OAAB19758)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "RBL2 Antibody (OAAB19758)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "128 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RBL2 Antibody (OAAB19758)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RBL2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RBL2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RBL2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RBL2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RBL2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RBL2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
