Catalog No: OAAB08424
Size:400ul
Price: $438.00
SKU
OAAB08424
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for OAAB08424
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationIF, WB
Additional InformationPrecautions: RASGRP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway
::Cellular Location: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome (Potential). Cell projection, ruffle membrane; Peripheral membrane protein (Potential). Note=Found both in the cytosol and associated with membranes. Isoform 2 mainly localizes to the cell membrane Enriched at juxtamembrane areas and membrane ruffles through association with F-actin. Localizes to th
Tissue Location: Detected in platelets, neutrophils and T lymphocytes (at protein level). Expressed in brain where it is enriched in the striatum. Also expressed in the hematopoietic system. Detected in heart, brain, lung, placenta, liver, skeletal muscle and kidney
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human RASGRP2.
Predicted Homology Based on Immunogen SequenceCow; Human; Mouse; Rat
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Sample Type Confirmation

RASGRP2 is supported by BioGPS gene expression data to be expressed in K562

Application InfoWB: 1:1000
IHC-P: 1:10~50
IF: 1:10~50
Gene SymbolRASGRP2
Alias SymbolsCDC25L, CALDAG-GEFI
NCBI Gene Id10235
Protein NameRAS guanyl-releasing protein 2
Description of TargetPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Uniprot IDQ7LDG7
Protein Accession #NP_001092140.1
Molecular Weight69248 Da
  1. What is the species homology for "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow".

  2. How long will it take to receive "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "RASGRP2 Antibody - N-terminal region (OAAB08424)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    This target may also be called "CDC25L, CALDAG-GEFI" in publications.

  5. What is the shipping cost for "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "69248 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RASGRP2 Antibody - N-terminal region (OAAB08424)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RASGRP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RASGRP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RASGRP2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RASGRP2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RASGRP2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RASGRP2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:RASGRP2 Antibody - N-terminal region (OAAB08424)
Your Rating
We found other products you might like!