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Catalog No: ARP56515_P050
Price: $0.00
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ARP56515_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-RASGRF1 (ARP56515_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RASGRF1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: PMSEKGKITRGRLGSLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNG
Concentration0.5 mg/ml
Blocking PeptideFor anti-RASGRF1 (ARP56515_P050) antibody is Catalog # AAP56515 (Previous Catalog # AAPP44487)
Gene SymbolRASGRF1
Gene Full NameRas protein-specific guanine nucleotide-releasing factor 1
Alias SymbolsGNRP, GRF1, CDC25, GRF55, CDC25L, H-GRF55, PP13187, ras-GRF1
NCBI Gene Id5923
Protein NameRas-specific guanine nucleotide-releasing factor 1
Description of TargetThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Uniprot IDQ13972
Protein Accession #NP_002882
Nucleotide Accession #NM_002891
Protein Size (# AA)1273
Molecular Weight145kDa
Protein InteractionsEHD4; SNRNP70; CEBPA; ADRBK1; MYC; UBC; TNK2; YWHAE; USP8; RAC1; PRKACA; NTRK2; RRAS2; NTRK3; NTRK1; RHOA; YWHAB; PPP1R9B; MARK3; HRAS;
  1. What is the species homology for "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RASGRF1 Antibody - middle region (ARP56515_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    This target may also be called "GNRP, GRF1, CDC25, GRF55, CDC25L, H-GRF55, PP13187, ras-GRF1" in publications.

  5. What is the shipping cost for "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "145kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RASGRF1 Antibody - middle region (ARP56515_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RASGRF1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RASGRF1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RASGRF1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RASGRF1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RASGRF1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RASGRF1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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