Catalog No: OPPA02353 (Formerly GWB-BSP600)
Size:2UG
Price: $75.00
SKU
OPPA02353
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RAN Protein (OPPA02353)

Datasheets/ManualsPrintable datasheet for OPPA02353
Product Info
Predicted Species ReactivityHuman
Product FormatRAN Human solution containing 20mM Tris HCL pH-8,1mM DTT & 10% glycerol. Physical appearance: Sterile filtered colorless solution.
HostE. Coli
::Product Introduction: RAN is a GTP-binding protein that participates in nucleocytoplasmic transport. RAN is necessary for the import of protein into the nucleus and also for RNA export. RAN takes part in chromatin condensation and control of cell cycle. The RAN complex with BIRC5 participates in mitotic spindle formation by being as a physical scaffold to assist the delivery of the RAN effector molecule TPX2 to microtubules. RUN increases AR-mediated transactivation.
Product Description: RAN Recombinant E.coli produced in E.Coli is a single, non-glycosylated polypeptide chain containing 236 amino acids (1-216 a.a.) and having a molecular mass of 26.5 kDa. The RAN is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Reconstitution and StorageRAN Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
PurityGreater than 90.0% as determined by SDS-PAGE.
Peptide SequenceMGSSHHHHHH SSGLVPRGSH MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL.
Gene SymbolRAN
Alias SymbolsTC4, Gsp1, ARA24
NCBI Gene Id5901
Protein NameGTP-binding nuclear protein Ran
Description of TargetRecombinant Human RAN, Member RAS Oncogene Family
Uniprot IDP62826
Protein Accession #NP_006316.1
Protein Size (# AA)Recombinant
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