RAN Protein (OPPA02353)

Catalog No: OPPA02353 (Formerly GWB-BSP600)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: RAN Human solution containing 20mM Tris HCL pH-8,1mM DTT & 10% glycerol. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: RAN is a GTP-binding protein that participates in nucleocytoplasmic transport. RAN is necessary for the import of protein into the nucleus and also for RNA export. RAN takes part in chromatin condensation and control of cell cycle. The RAN complex with BIRC5 participates in mitotic spindle formation by being as a physical scaffold to assist the delivery of the RAN effector molecule TPX2 to microtubules. RUN increases AR-mediated transactivation.
  Product Description: RAN Recombinant E.coli produced in E.Coli is a single, non-glycosylated polypeptide chain containing 236 amino acids (1-216 a.a.) and having a molecular mass of 26.5 kDa. The RAN is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: RAN Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL.

Target Info

• Gene Symbol: RAN
• Alias Symbols: TC4, Gsp1, ARA24
• NCBI Gene Id: 5901
• Protein Name: GTP-binding nuclear protein Ran
• Description of Target: Recombinant Human RAN, Member RAS Oncogene Family
• Uniprot ID: P62826
• Protein Accession #: NP_006316.1
• Protein Size (# AA): Recombinant