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RAD51 Antibody (OAGA08778)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human, Mouse, Chicken, Rat
Product Format:
Liquid PBS
Clonality:
Monoclonal
Clone:
14B4
Isotype:
IgG2b,k
Host:
Mouse
Application:
ICC, IF, IHC-P, IP, WB
:::
Positive Controls: Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2
Reconstitution and Storage:
Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
Immunogen:
Full length (amino acids 1-338) Rad51 expressed in E. coli.
Purification:
Affinity purified by Protein A.
Concentration:
1.8 mg/ml
Datasheets/Manuals:
Printable datasheet for OAGA08778
Application Info:
WB: 1:500~3000
ICC/IF: 1:300
IHC: 1:100~150
IP: Follow recommended protocol. Not tested in other applications.
Gene Symbol:
RAD51
Official Gene Full Name:
RAD51 recombinase
Alias Symbols:
RECA, BRCC5, FANCR, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930
NCBI Gene Id:
5888
Protein Name:
DNA repair protein RAD51 homolog 1
Description of Target:
Rad51, a 37 kDa protein, is the human homologue of E. coli RecA protein and a member of the RAD52 epistasis group in S. cerevisiae. In recent studies it has been reported that BRCA1 interacts with Rad51 and disease-causing mutations have been found in the BRCA1 region necessary for BRCA1/Rad51 interaction, implying that this interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact by direct binding of the BRC repeats located within exon 11 of BRCA2. When these repeats are deleted, the interaction is lost and cells become hypersensitive to the DNA damage caused by methyl methanesulfonate (MMS).
Swissprot Id:
Q06609
Protein Accession #:
NP_001157741.1
Nucleotide Accession #:
NM_001164269.1
Molecular Weight:
37 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RAD51.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RAD51.

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