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RAD51 Antibody (OAGA01298)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid. 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IF, IHC-P, IP, WB
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-36360 from Santa Cruz Biotechnology.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Rad51. The exact sequence is proprietary.
Concentration:
0.57mg/ml
Datasheets/Manuals:
Printable datasheet for anti-RAD51 (OAGA01298) antibody
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000, IP: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene Symbol:
RAD51
Official Gene Full Name:
RAD51 recombinase
Alias Symbols:
RECA, BRCC5, FANCR, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930
NCBI Gene Id:
5888
Description of Target:
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot Id:
Q06609
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported to express RAD51.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RAD51.

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