Size:100 ul
$329.00
In Stock
SKU
OAAB22017
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More Information
Predicted Species Reactivity Human, Mouse
Product Format Liquid
Clonality Monoclonal
Host Rabbit
Application WB
Additional Information Function: Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-36360 from Santa Cruz Biotechnology.
Predicted Homology Based on Immunogen Sequence Human, Mouse
Datasheets/Manuals Printable datasheet for anti-RAD51 (OAAB22017) antibody
Preservative 0.03% Proclin300 and 50% glycerol
Formulation 0.03% Proclin300 and 50% glycerol.
Application Info WB: 1:1000
Target Reference Shinohara A.,et al.Nat. Genet. 4:239-243(1993).
Yoshimura Y.,et al.Nucleic Acids Res. 21:1665-1665(1993).
Schmutte C.,et al.Cancer Res. 59:4564-4569(1999).
Wang W.W.,et al.Cancer Epidemiol. Biomarkers Prev. 10:955-960(2001).
Park J.Y.,et al.Nucleic Acids Res. 36:3226-3234(2008).
Gene Symbol RAD51
Official Gene Full Name RAD51 recombinase
Alias Symbols RECA, BRCC5, FANCR, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930
NCBI Gene Id 5888
Description of Target The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot Id Q06609
Protein Accession # NP_001157741.1
Nucleotide Accession # NM_001164269.1
Molecular Weight 37 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RAD51.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RAD51.
  1. What is the species homology for "RAD51 Antibody (OAAB22017)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "RAD51 Antibody (OAAB22017)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "RAD51 Antibody (OAAB22017)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RAD51 Antibody (OAAB22017)"?

    This target may also be called "RECA, BRCC5, FANCR, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930" in publications.

  5. What is the shipping cost for "RAD51 Antibody (OAAB22017)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RAD51 Antibody (OAAB22017)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RAD51 Antibody (OAAB22017)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RAD51 Antibody (OAAB22017)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RAD51"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RAD51"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RAD51"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RAD51"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RAD51"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RAD51"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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