RAD51 Antibody (OAAB17790)

Catalog No: OAAB17790

Size:400ul

Western blot analysis of lysates from Jurkat, Hela, mouse NIH/3T3, rat C6, PC-12 cell line (from left to right), using RAD51 Antibody (Cat. #OAAB17790).
OAAB17790 was diluted at 1:1000 at each lane.
A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody.
Lysates at 35ug per lane.
Dilution: 1:1000

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Host: Mouse
• Application: WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This RAD51 antibody is generated from a mouse immunized with a recombination protein from human.
• Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
• Application Info: WB: 1:1000
• Reference: Shinohara A., et al.Nat. Genet. 4:239-243(1993).
  Yoshimura Y., et al.Nucleic Acids Res. 21:1665-1665(1993).
  Schmutte C., et al.Cancer Res. 59:4564-4569(1999).
  Wang W.W., et al.Cancer Epidemiol. Biomarkers Prev. 10:955-960(2001).
  Park J.Y., et al.Nucleic Acids Res. 36:3226-3234(2008).

Target Info

• Gene Symbol: RAD51
• Alias Symbols: RECA, BRCC5, FANCR, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930
• NCBI Gene Id: 5888
• Description of Target: Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
• Uniprot ID: Q06609
• Molecular Weight: 37 kDa