Catalog No: ARP42211_T100
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ARP42211_T100
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Datasheets/ManualsPrintable datasheet for anti-RAD23A (ARP42211_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RAD23A
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: GIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQFQNMRQVIQQ
Concentration1.0 mg/ml
Blocking PeptideFor anti-RAD23A (ARP42211_T100) antibody is Catalog # AAP42211 (Previous Catalog # AAPP24634)
Sample Type Confirmation

RAD23A is supported by BioGPS gene expression data to be expressed in Jurkat

ReferenceJu,D. (2006) Biochem. Biophys. Res. Commun. 341 (2), 648-652
Publications

USF-1 is critical for maintaining genome integrity in response to UV-induced DNA photolesions. PLoS Genet. 8, e1002470 (2012). 22291606

Description
Gene SymbolRAD23A
Gene Full NameRAD23 homolog A (S. cerevisiae)
Alias SymbolsHR23A, HHR23A
NCBI Gene Id5886
Protein NameUV excision repair protein RAD23 homolog A
Description of TargetRAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Uniprot IDP54725
Protein Accession #NP_005044
Nucleotide Accession #NM_005053
Protein Size (# AA)363
Molecular Weight40kDa
Protein InteractionsUSP25; ZBTB44; TRIP6; TRAF5; TRAF2; ZBTB8A; ANKRD40; FAM188A; TRIM54; NGLY1; CEP250; CEP76; UBC; SHFM1; vpr; XPC; DCTPP1; OGFOD1; UBA6; UBE2R2; TRNT1; HERC4; NT5C2; FKBP9; PCNA; HEXA; CDC34; GNPDA1; GTF3C4; USP5; WARS; TBCE; PYGL; PARP1; SH3RF2; PARK2; SQ
  1. What is the species homology for "RAD23A Antibody - middle region (ARP42211_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "RAD23A Antibody - middle region (ARP42211_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RAD23A Antibody - middle region (ARP42211_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RAD23A Antibody - middle region (ARP42211_T100)"?

    This target may also be called "HR23A, HHR23A" in publications.

  5. What is the shipping cost for "RAD23A Antibody - middle region (ARP42211_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RAD23A Antibody - middle region (ARP42211_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RAD23A Antibody - middle region (ARP42211_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "40kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RAD23A Antibody - middle region (ARP42211_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RAD23A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RAD23A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RAD23A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RAD23A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RAD23A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RAD23A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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