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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for Rad17 Antibody (OAAF00698) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Reconstitution and Storage | -20°C |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAD17. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Specificity | Rad17 (Ab-645) antibody detects endogenous levels of total Rad17 protein. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Application Info | WB: 1:500~1:3000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:10000 |
| Reference | Sean Post, PNAS, Nov 2001; 98: 13102. Lee Zou, Genes & Dev., Jan 2002; 16: 198. Renu Garg, Mol. Cancer Res., Jun 2004; 2: 362 – 369. |
| Gene Symbol | RAD17 |
|---|---|
| Gene Full Name | RAD17 checkpoint clamp loader component |
| Alias Symbols | CCYC;cell cycle checkpoint protein (RAD17);cell cycle checkpoint protein RAD17;HRAD17;R24L;RAD1 homolog;RAD17 homolog;Rad17-like protein;RAD17SP;RAD24;RF-C activator 1 homolog;RF-C/activator 1 homolog. |
| NCBI Gene Id | 5884 |
| Protein Name | Cell cycle checkpoint protein RAD17 |
| Description of Target | Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination. |
| Uniprot ID | O75943 |
| Protein Accession # | NP_002864.1 |
| Molecular Weight | 77 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Rad17 Antibody (OAAF00698)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "Rad17 Antibody (OAAF00698)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "Rad17 Antibody (OAAF00698)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Rad17 Antibody (OAAF00698)"?
This target may also be called "CCYC;cell cycle checkpoint protein (RAD17);cell cycle checkpoint protein RAD17;HRAD17;R24L;RAD1 homolog;RAD17 homolog;Rad17-like protein;RAD17SP;RAD24;RF-C activator 1 homolog;RF-C/activator 1 homolog." in publications.
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What is the shipping cost for "Rad17 Antibody (OAAF00698)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Rad17 Antibody (OAAF00698)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Rad17 Antibody (OAAF00698)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "77 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Rad17 Antibody (OAAF00698)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RAD17"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RAD17"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RAD17"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RAD17"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RAD17"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RAD17"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
