RAC2 Protein (OPPA02209)

Catalog No: OPPA02209 (Formerly GWB-BD2A95)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The RAC2 solution contains 20mM Tris-HCl buffer (pH 8.0), 20% Glycerol, 2mM EDTA, 2mM DTT and 0.1M NaCl. Physical appearance: Sterile Filtered colorless solution.
• Host: E. Coli
  Product Introduction: RAC2 is a small signaling G protein/GTPase which is part of the RAS superfamily of small GTP-binding proteins which regulate cell growth, actin cytoskeletal organization, cell proliferation, survival, cell cycle progression, gene transcription rgulation and the activation of protein kinases. RAC2 cycles between an active gtp-bound and inactive gdp-bound state. In active state, RAC2 binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 is involved in the regulation of the nadph oxidase.
  Product Description: RAC2 Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 209 amino acids (1- 189 a.a.) and having a molecular mass of 23.3kDa.The RAC2 is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: RAC2 although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC.

Target Info

• Gene Symbol: RAC2 (189)
• Alias Symbols: Gx, EN-7, IMD73A, IMD73B, IMD73C, HSPC022, p21-Rac2
• NCBI Gene Id: 5880
• Protein Name: Ras-related C3 botulinum toxin substrate 2
• Description of Target: Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2 (1-189)
• Uniprot ID: P15153
• Protein Accession #: NP_002863.1
• Protein Size (# AA): Recombinant