RAB1A Recombinant Protein (OPCD00245)

Catalog No: OPCD00245 (Formerly GWB-79F2P1)

RAB1A Recombinant Protein (OPCD00245) using SDS-PAGE

RAB1A Recombinant Protein (OPCD00245) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Isoelectric Point: 5.9
  Subcellular Location: Golgi apparatus
  Residues: Ser2-Cys205
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: RAB1A
• Gene Full Name: RAB1A, member RAS oncogene family
• Alias Symbols: GTP binding protein Rab1a;Rab GTPase YPT1 homolog;RAB1;RAB1, member RAS oncogene family;ras-related protein Rab-1A;YPT1;YPT1-related protein.
• NCBI Gene Id: 5861
• Protein Name: Ras-related protein Rab-1A
• Description of Target: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.
• Uniprot ID: P62820
• Protein Accession #: NP_004152.1
• Nucleotide Accession #: NM_004161.4
• Protein Size (# AA): Ser2~Cys205
• Molecular Weight: 26kDa