QKI (pan) Antibody : FITC (OASE00313-FITC)

Catalog No: OASE00313-FITC

Size:100ug

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Monoclonal
• Clone: S147-6
• Isotype: IgG2b
• Host: Mouse
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB, ICC, IHC
• Additional Information: Background Info: Detects a 36-38 kDa protein corresponding to the molecular weight of Pan-QKI
  Scientific Background: QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.
  Certificate of Analysis: 1ug/mL was sufficient for detection of Pan-QKI in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: Fusion protein amino acids 1-341 (full-length) of human QKI-5 (accession number Q96PU8)
  Mouse: 100% identity (341/341 amino acids identical)
  Rat: 99% identity (339/341 amino acids identical)
  >90% identity with QKI-6, QKI-7 and QKI-7b
  
• Purification: Protein G Purified
• Concentration: 1 mg/ml
• Dilution: 1:1000 WB
• Storage Buffer: PBS pH 7.4, 50% glycerol, 0.1% sodium azide

Target Info

• Gene Symbol: QKI
• Gene Full Name: QKI, KH domain containing, RNA binding
• Alias Symbols: QK, Hqk, QK1, QK3, hqkI
• NCBI Gene Id: 9444
• Uniprot ID: Q96PU8
• Protein Accession #: NP_006766.1.