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| Datasheets/Manuals | Printable datasheet for anti-PTPRZ1 (OASG06131) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat |
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| Product Format | Liquid.PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | WB |
| Additional Information | Cellular Localization: Isoform 1: Cell membrane. Single-pass type I membrane protein. Secreted. A secreted form is apparently generated by shedding of the extracellular domain. Isoform 2: Secreted Tissue Specificity: Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain. |
| Reconstitution and Storage | Store at -20C, and avoid repeat freeze-thaw cycles. |
| Immunogen | Synthesized peptide derived between 100-180 aa from N-terminal region of human PTPzeta. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Specificity | PTPzeta Polyclonal Antibody detects endogenous levels of PTPzeta protein. |
| Application Info | WB: 1:500-1:2000 ELISA: 1:5000 Optimal dilutions should be determined by the end user. |
| Gene Symbol | PTPRZ1 |
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| Gene Full Name | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| Alias Symbols | PTPZ, HPTPZ, PTP18, PTPRZ, RPTPB, HPTPzeta, PTP-ZETA, RPTPbeta, phosphacan, R-PTP-zeta-2 |
| NCBI Gene Id | 5803 |
| Description of Target | Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades . |
| Uniprot ID | P23471 |
| Molecular Weight | 250 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "PTPRZ1 Antibody - N-terminal region (OASG06131)" provided in?
This item is provided in "Liquid.PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
This target may also be called "PTPZ, HPTPZ, PTP18, PTPRZ, RPTPB, HPTPzeta, PTP-ZETA, RPTPbeta, phosphacan, R-PTP-zeta-2" in publications.
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What is the shipping cost for "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "250 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PTPRZ1 Antibody - N-terminal region (OASG06131)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PTPRZ1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PTPRZ1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PTPRZ1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PTPRZ1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PTPRZ1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PTPRZ1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
