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PTPRC Recombinant Protein (OPCD06515)

Catalog#: OPCD06515
Domestic: within 1-2 weeks delivery | International: 1-2 weeks
More Information
Predicted Species Reactivity Human
Product Format Lyophilized
Host E.coli
Conjugation Unconjugated
Application SDS-PAGE, WB, ELISA, IP
Additional Information Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
:: Residues: Asp193-Lys575
:: Subcellular Location: Membrane; Single-pass type I membrane protein. Membrane raf
Reconstitution and Storage Reconstitute in PBS or others.
Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
Formulation PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Purity > 95%
Source Prokaryotic Expressed Recombinant
Tag N-terminal His Tag
Datasheets/Manuals Printable datasheet for OPCD06515
Gene Symbol PTPRC
Official Gene Full Name protein tyrosine phosphatase, receptor type C
Alias Symbols B220, CD45, CD45R, GP180, LCA, L-CA, Leukocyte common antigen, LY5, Receptor-type tyrosine-protein phosphatase C, T200
NCBI Gene Id 5788
Protein Name Receptor-type tyrosine-protein phosphatase C
Description of Target Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Swissprot Id P08575
Protein Accession # NP_002829.3
Nucleotide Accession # NM_002838.4
Molecular Weight 45 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express PTPRC.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express PTPRC.
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