Catalog No: OPCD06515
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OPCD06515
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Datasheets/ManualsPrintable datasheet for PTPRC Recombinant Protein (OPCD06515)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Asp193-Lys575
::Subcellular Location: Membrane; Single-pass type I membrane protein. Membrane raf
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPTPRC
Gene Full Nameprotein tyrosine phosphatase, receptor type C
Alias SymbolsLCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180
NCBI Gene Id5788
Protein NameProtein tyrosine phosphatase receptor type C
Description of TargetProtein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Uniprot IDP08575
Protein Accession #NP_002829.3
Nucleotide Accession #NM_002838.4
Protein Size (# AA)Asp193~Lys575
Molecular Weight44kDa
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