Size:100 ug
$109.00
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OATA00160
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PTPRC Antibody : Biotin (OATA00160)

Catalog#: OATA00160
Domestic: within 1 week delivery | International: 1 week
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Chimpanzee
Product Format Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2
Clonality Monoclonal
Clone UCHL1
Isotype Mouse IgG2a, kappa
Host Mouse
Conjugation Biotin
Application FC, IHC-F, IHC-P, IF, IP, WB
Reconstitution and Storage 2-8C protected from light
Datasheets/Manuals Printable datasheet for OATA00160
Specificity CD45RO
Application Info This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
Target Reference

Imanguli MM, Swaim WD, League SC, Gress RE, Pavletic SZ, and Hakim FT. 2009. Blood. 113: 3620-3630. (Immunohistochemistry - paraffin embedded tissue)

Di Carlo E, D"™Antuono T, Pompa P, Giuliani R, Rosini S, Stuppia L, Musiani P, and Sorrentino C. 2009. Clin. Cancer Res. 15: 2979-2987. (Immunohistochemistry - paraffin embedded tissue)

Kap YS, van Meurs M, van Driel N, Koopman G, Melief M-J, Brok HPM, Laman JD, and "˜t Hart BA. 2009. J.Histochemistry & Cytochemistry. 57: 1159-1167. (Immunohistochemistry - Chimpanzee frozen tissue)

Bonzheim I, Geissinger E, Tinguely M, Roth S, Grieb T, Reimer P, Wilhelm M, Rosenwald A, Muller-Hermelink HK, and Rudiger T. 2008. Am. J. Clin. Pathol. 130: 613-619. (Immunofluorescence microscopy - frozen tissue)

Kim M-H, Suh H-S, Si Q, Terman BE, and Lee SC. 2006. J. Virol. 80: 62-72. (Western Blot)

Cappione AJ, Pugh-Bernard AE, Anolik JH, and Sanz I. 2004. J. Immunol. 172: 4298-4307. (Immunoprecipitation)

Gougeon ML, Lecoeur H, Boudet F, Ledru E. Marzabal S, Boullier S, Roue R, Nagata S, and Heeney J. 1997. J. Immunol. 158: 2964-2976. (Flow cytometry - Chimpanzee)

Kulas DT, Freund GG, and Mooney RA. 1996. J. Biol. Chem. 271: 755-760. (Immunoprecipitation, Western Blot)

Gene Symbol PTPRC
Official Gene Full Name protein tyrosine phosphatase receptor type C
Alias Symbols LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180
NCBI Gene Id 5788
Protein Name receptor-type tyrosine-protein phosphatase C
Description of Target The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Swissprot Id P08575
Protein Accession # NP_002829.3
Nucleotide Accession # NM_002838.4
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express PTPRC.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express PTPRC.
  1. What is the species homology for "PTPRC Antibody : Biotin (OATA00160)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Chimpanzee".

  2. How long will it take to receive "PTPRC Antibody : Biotin (OATA00160)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "PTPRC Antibody : Biotin (OATA00160)" provided in?

    This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PTPRC Antibody : Biotin (OATA00160)"?

    This target may also be called "LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180" in publications.

  5. What is the shipping cost for "PTPRC Antibody : Biotin (OATA00160)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PTPRC Antibody : Biotin (OATA00160)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PTPRC Antibody : Biotin (OATA00160)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PTPRC Antibody : Biotin (OATA00160)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "PTPRC"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PTPRC"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PTPRC"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PTPRC"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PTPRC"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PTPRC"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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