- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for PTPN1 Antibody (OAAF00958) |
|---|
| Predicted Species Reactivity | Human|Monkey|Mouse|Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Reconstitution and Storage | -20°C |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PTP1B. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Specificity | PTP1B (Ab-50) antibody detects endogenous levels of total PTP1B protein. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Application Info | WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:20000 |
| Reference | Gang Xu, J. Biol. Chem., Dec 2002; 277: 49989 - 49997. Yinges Yigzaw, J. Biol. Chem., Jan 2003; 278: 284 - 288. Jinseol Rhee, J. Biol. Chem., Feb 2001; 276: 6640 - 6644. Fawaz G. Haj, Science, Mar 2002; 295: 1708 |
| Gene Symbol | PTPN1 |
|---|---|
| Gene Full Name | protein tyrosine phosphatase non-receptor type 1 |
| Alias Symbols | protein tyrosine phosphatase, placental;protein-tyrosine phosphatase 1B;PTP1B;tyrosine-protein phosphatase non-receptor type 1. |
| NCBI Gene Id | 5770 |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 1 |
| Description of Target | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. |
| Uniprot ID | P18031 |
| Protein Accession # | NP_002818.1 |
| Molecular Weight | 49 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "PTPN1 Antibody (OAAF00958)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Monkey|Mouse|Rat".
-
How long will it take to receive "PTPN1 Antibody (OAAF00958)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
-
What buffer format is "PTPN1 Antibody (OAAF00958)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PTPN1 Antibody (OAAF00958)"?
This target may also be called "protein tyrosine phosphatase, placental;protein-tyrosine phosphatase 1B;PTP1B;tyrosine-protein phosphatase non-receptor type 1." in publications.
-
What is the shipping cost for "PTPN1 Antibody (OAAF00958)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "PTPN1 Antibody (OAAF00958)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "PTPN1 Antibody (OAAF00958)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "49 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PTPN1 Antibody (OAAF00958)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "PTPN1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "PTPN1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "PTPN1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "PTPN1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "PTPN1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "PTPN1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
