PTN Recombinant Protein (OPCD06508)

Catalog No: OPCD06508

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly33-Asp168
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Ptn
• Gene Full Name: pleiotrophin
• Alias Symbols: HARP;HBBM;HBBN;HB-GA;HB-GAM;HBGF-8;HBN;HBNF;heparin-binding brain mitogen;heparin-binding growth factor 8;heparin-binding growth-associated molecule;heparin-binding neutrophic factor;Os;OSF;Osf1;Osf-1;osteoblast-specific factor 1;pleiotrophin.
• NCBI Gene Id: 19242
• Protein Name: Pleiotrophin
• Description of Target: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. Binds to cell-surface target proteins via their chondroitin sulfate groups. Down-regulates PTPRZ1 activity.
• Uniprot ID: P63089
• Protein Accession #: NP_032999.1
• Nucleotide Accession #: NM_008973.2
• Protein Size (# AA): Gly33~Asp168
• Molecular Weight: 18kDa