PTN Recombinant Protein (OPCD06506)

Catalog No: OPCD06506

PTN Recombinant Protein (OPCD06506) using SDS-PAGE

PTN Recombinant Protein (OPCD06506) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Bos taurus|Bovine
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly33-Asp168
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: PTN
• Gene Full Name: pleiotrophin
• Alias Symbols: HBBM;HB-GAM;HBGF-8;heparin binding growth factor 8;heparin-binding brain mitogen;Heparin-binding growth factor 8;heparin-binding growth-associated molecule;heparin-binding neurite-promoting factor;neurite growth-promoting factor 1;p18;pleiotrophin;pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1).
• NCBI Gene Id: 280904
• Protein Name: Pleiotrophin
• Description of Target: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1550956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. Binds to cell-surface target proteins via their chondroitin sulfate groups. Down-regulates PTPRZ1 activity.
• Uniprot ID: P21782
• Protein Accession #: NP_776380.1
• Nucleotide Accession #: NM_173955.1
• Protein Size (# AA): Gly33~Asp168
• Molecular Weight: 18kDa