PTGS1 Recombinant Protein (OPCD06482)

Catalog No: OPCD06482

PTGS1 Recombinant Protein (OPCD06482) using SDS-PAGE

PTGS1 Recombinant Protein (OPCD06482) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly367-Leu599
  Subcellular Location: Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membran
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: PTGS1
• Gene Full Name: prostaglandin-endoperoxide synthase 1
• Alias Symbols: COX1;COX3;cyclooxygenase-1;PCOX1;PES-1;PGG/HS;PGH synthase 1;PGHS1;PGHS-1;PHS1;prostaglandin G/H synthase 1;prostaglandin H2 synthase 1;Prostaglandin-endoperoxide synthase 1;prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase);PTGHS.
• NCBI Gene Id: 5742
• Protein Name: Prostaglandin G/H synthase 1
• Description of Target: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
• Uniprot ID: P23219
• Protein Accession #: NP_000953.2
• Nucleotide Accession #: NM_000962.3
• Protein Size (# AA): Gly367~Leu599
• Molecular Weight: 30kDa