PTCH1 Recombinant Protein (OPCD06471)

Catalog No: OPCD06471

PTCH1 Recombinant Protein (OPCD06471) using SDS-PAGE

PTCH1 Recombinant Protein (OPCD06471) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu227-Asp436
  Subcellular Location: Membrane
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: PTCH1
• Gene Full Name: patched 1
• Alias Symbols: BCNS;NBCCS;protein patched homolog 1;PTC;PTC1;PTCH.
• NCBI Gene Id: 5727
• Protein Name: Protein patched homolog 1
• Description of Target: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
• Uniprot ID: Q13635
• Protein Accession #: NP_000255.2
• Nucleotide Accession #: NM_000264.3
• Protein Size (# AA): Leu227~Asp436
• Molecular Weight: 26kDa