PSMC3 Antibody (OACD06766)

Catalog No: OACD06766

Western Blot with Human Recombinant PSMC3

Western Blot; Lane 1: Human 293T cells; Lane 2: Human Hela Cells; Lane 3: Human HepG2 cells; Lane 4: Human Saliva Tissue.

DAB staining on formalin fixed paraffin-embedded Kidney tissue

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC, WB
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Range: Asn2 - Ala439
• Purification: Affinity Purified; Protein A Purified
• Concentration: 0.41 mg/ml
• Preservative: 0.02% NaN3
• Specificity: The antibody is a rabbit polyclonal antibody raised against PSMC3. It has been selected for its ability to recognize PSMC3 in immunohistochemical staining and western blotting.
• Formulation: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
• Application Data: Western blotting: 1:50-400
  Immunocytochemistry in formalin fixed cells: 1:50-500
  Immunohistochemistry in formalin fixed frozen section: 1:50-500
  Immunohistochemistry in paraffin section: 1:10-100
  Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
  Optimal working dilutions must be determined by end user.

Target Info

• Gene Symbol: PSMC3
• Gene Full Name: proteasome 26S subunit, ATPase 3
• Alias Symbols: 26S protease regulatory subunit 6A;26S proteasome AAA-ATPase subunit RPT5;26S proteasome regulatory subunit 6A;DCIDP;human immunodeficiency virus tat transactivator binding protein-1;proteasome (prosome, macropain) 26S subunit, ATPase, 3;Proteasome 26S subunit ATPase 3;proteasome subunit P50;RPT5;Tat-binding protein 1;TBP1;testicular secretory protein Li 42.
• NCBI Gene Id: 5702
• Protein Name: 26S proteasome regulatory subunit 6A
• Description of Target: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
• Uniprot ID: P17980
• Protein Accession #: NP_002795.2
• Nucleotide Accession #: NM_002804
• Molecular Weight: 49 kDa