Size:100 ul
$329.00
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SKU
OAGA01026
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PSMB8 Antibody (OAGA01026)

Catalog#: OAGA01026
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application ICC, IF, IHC-FFPE, WB
Additional Information Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq]
:: Positive Controls: A431, Molt-4, Raji
:: Cellular Localization: Cytoplasm (By similarity), Nucleus
Reconstitution and Storage Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item This antibody may replace item sc-100284 from Santa Cruz Biotechnology.
Immunogen Recombinant fragment corresponding to a region within amino acids 52 and 276 of PSMB8 (Uniprot ID#P28062)
Purification Purified by antigen-affinity chromatography.
Concentration 0.38 mg/ml
Datasheets/Manuals Printable datasheet for anti-PSMB8 antibody - OAGA01026
Application Info Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol PSMB8
Official Gene Full Name Proteasome subunit beta type-8
Alias Symbols D6S216 antibody, D6S216E antibody, LMP7 antibody, MGC1491 antibody, PSMB5i antibody, RING10 antibody, PSMB8 antibody, proteasome subunit Y2 antibody, macropain subunit C13 antibody, proteasome subunit beta type-8 antibody, really interesting new gene 10 p
NCBI Gene Id 5696
Protein Name Proteasome subunit beta type-8
Swissprot Id P28062
Protein Accession # NP_004150.1
Molecular Weight 30 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express PSMB8.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express PSMB8.
  1. What is the species homology for "PSMB8 Antibody (OAGA01026)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "PSMB8 Antibody (OAGA01026)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "PSMB8 Antibody (OAGA01026)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PSMB8 Antibody (OAGA01026)"?

    This target may also be called "D6S216 antibody, D6S216E antibody, LMP7 antibody, MGC1491 antibody, PSMB5i antibody, RING10 antibody, PSMB8 antibody, proteasome subunit Y2 antibody, macropain subunit C13 antibody, proteasome subunit beta type-8 antibody, really interesting new gene 10 p" in publications.

  5. What is the shipping cost for "PSMB8 Antibody (OAGA01026)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PSMB8 Antibody (OAGA01026)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PSMB8 Antibody (OAGA01026)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "30 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PSMB8 Antibody (OAGA01026)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "PSMB8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PSMB8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PSMB8"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PSMB8"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PSMB8"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PSMB8"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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