PSMB2 Antibody - middle region (ARP56461_P050)

Catalog No: ARP56461_P050

WB Suggested Anti-PSMB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysatePSMB2 is supported by BioGPS gene expression data to be expressed in HepG2

Host: Rabbit
Target Name: PSMB2
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: PSMB2
Sample Type: Hela
Antibody Dilution: 1.0ug/mlPSMB2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells

Host: Rabbit
Target Name: PSMB2
Sample Type: 293T
Antibody Dilution: 1.0ug/mlPSMB2 is supported by BioGPS gene expression data to be expressed in HEK293T

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSMB2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: YDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERA
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PSMB2 (ARP56461_P050) antibody is Catalog # AAP56461 (Previous Catalog # AAPP35408)
• Sample Type Confirmation:

  PSMB2 is strongly supported by BioGPS gene expression data to be expressed in HeLa

  PSMB2 is supported by BioGPS gene expression data to be expressed in HEK293T, HepG2

• Subunit: beta type-2

Target Info

• Reference: Gregory,S.G., (2006) Nature 441 (7091), 315-321
• Gene Symbol: PSMB2
• Gene Full Name: Proteasome (prosome, macropain) subunit, beta type, 2
• Alias Symbols: HC7-I
• NCBI Gene Id: 5690
• Protein Name: Proteasome subunit beta type-2
• Description of Target: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P49721
• Protein Accession #: NP_002785
• Nucleotide Accession #: NM_002794
• Protein Size (# AA): 201
• Molecular Weight: 23kDa
• Protein Interactions: KCTD9; UBC; KRT13; PSMD14; ASB11; POMP; PSMB8; PSMB7; PSMB6; PSMB5; PYCRL; PSMB4; PSMB3; PSMB1; PSMA7; PSMA6; PSMA5; PSMA4; PSMA3; PSMA1; HOXA2; PSMA2; PARK2; CDK20; ITGA4; GPX2; FN1; DDX49; IQCB1; VCAM1; SULT1A4; TUBB; PSMA8; C11orf58; SEC23A; PSME3; PSM