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PSMA6 Antibody (OAGA01024)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, IHC-FFPE, WB
Additional Information:
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]
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Positive Controls: 293T, A431, H1299, HeLa, mouse liver, rat liver
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Cellular Localization: Cytoplasm, Nucleus
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-271187 from Santa Cruz Biotechnology.
Immunogen:
Recombinant fragment contain a sequence corresponding to a region within amino acids 57 and 274 of Proteasome 20S alpha 6
Purification:
Purified by antigen-affinity chromatography.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-PSMA6 antibody - OAGA01024
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
PSMA6
Official Gene Full Name:
Proteasome subunit alpha type-6
Alias Symbols:
IOTA antibody, MGC22756 antibody, MGC2333 antibody, MGC23846 antibody, PROS27 antibody, p27K antibody, PSMA6 antibody, 27 kDa prosomal protein antibody, multicatalytic endopeptidase complex iota chain antibody, macropain iota chain antibody, prosomal P27K
NCBI Gene Id:
5687
Protein Name:
Proteasome subunit alpha type-6
Swissprot Id:
P60900
Protein Accession #:
NP_002782.1
Molecular Weight:
27 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PSMA6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PSMA6.

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