Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OAAN02386
Price: $0.00
SKU
OAAN02386
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for anti-PSEN2 (OAAN02386)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenA synthetic peptide of human PSEN2
PurificationAffinity purified against immunogen
Preservative0.02% Sodium Azide
Application InfoWB: 1:500 - 1:2,000. IHC: 1:50 - 1:200
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene SymbolPSEN2
Gene Full Namepresenilin 2
Alias SymbolsAD4, PS2, AD3L, STM2, CMD1V
NCBI Gene Id5664
Protein NamePresenilin-2
Description of TargetAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.
Uniprot IDP49810
Protein Accession #NP_000438.2
Nucleotide Accession #NM_000447.2
Molecular Weight50 kDa
  1. What is the species homology for "PSEN2 Antibody (OAAN02386)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "PSEN2 Antibody (OAAN02386)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "PSEN2 Antibody (OAAN02386)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PSEN2 Antibody (OAAN02386)"?

    This target may also be called "AD4, PS2, AD3L, STM2, CMD1V" in publications.

  5. What is the shipping cost for "PSEN2 Antibody (OAAN02386)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PSEN2 Antibody (OAAN02386)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PSEN2 Antibody (OAAN02386)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "50 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PSEN2 Antibody (OAAN02386)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PSEN2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PSEN2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PSEN2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PSEN2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PSEN2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PSEN2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:PSEN2 Antibody (OAAN02386)
Your Rating
We found other products you might like!