Search Antibody, Protein, and ELISA Kit Solutions

PSEN1 Antibody (OAPB00522)

0.1 mg
$375.00
In Stock
Request Bulk Order Quote

Conjugation Options

OAPB00522-FITC Conjugated

OAPB00522-HRP Conjugated

OAPB00522-Biotin Conjugated

Gene Symbol:
PSEN1
Official Gene Full Name:
Presenilin-1
NCBI Gene Id:
5663
Protein Name:
Presenilin-1
Swissprot Id:
P49768
Replacement Item:
This antibody may replace item sc-122767 from Santa Cruz Biotechnology.
Description of Target:
a gamma-secretase subunit
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity chromatography purified via peptide column
Application:
ELISA, WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PSEN1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PSEN1.
Immunogen:
The immunogen for anti-Presenilin1 antibody: antibody was raised against a 23 amino acid peptide from near the carboxy terminus of human presenilin1.
Predicted Species Reactivity:
Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Rat
Reconstitution and Storage:
Presenilin1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Blocking Peptide:
For anti-PSEN1 (OAPB00522) antibody is Catalog # OEPB02642
Datasheets/Manuals:
Printable datasheet for anti-PSEN1 (OAPB00522) antibody
Application Info:
Presenilin1 antibody can be used for detection of presenilin1 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
:::
Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Target Reference:
Sherrington R, Rogaev EI, Liang Y, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer’s disease. Nature1995; 375:754-60.;Weihofen A and Martoglio B. Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides. Trends Cell Biol.2003; 13:71-8.;Periz G and Fortini ME. Functional reconstitution of g-secretase through coordinated expression of presenilin, nicastrin, aph-1, and pen-2. J. Neurosci. Res.2004; 77:309-22.;Selkoe DJ. The cell biology of b-amyloid precursor protein and presenilin in Alzheimer’s disease. Trends Cell Biol.1998; 8:447-53.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...