Size:0.1 mg
$339.00
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SKU
OAPB00522
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Conjugation Options

OAPB00522-FITC Conjugated

OAPB00522-HRP Conjugated

OAPB00522-Biotin Conjugated

PSEN1 Antibody (OAPB00522)

Catalog#: OAPB00522
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Application WB, IHC
:: Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and Storage Presenilin1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Replacement Item This antibody may replace item sc-122767 from Santa Cruz Biotechnology.
Immunogen The immunogen for anti-Presenilin1 antibody: antibody was raised against a 23 amino acid peptide from near the carboxy terminus of human presenilin1.
Purification Affinity chromatography purified via peptide column
Predicted Homology Based on Immunogen Sequence Human; Mouse; Rat
Blocking Peptide For anti-PSEN1 (OAPB00522) antibody is Catalog # OEPB02642
Datasheets/Manuals Printable datasheet for anti-PSEN1 (OAPB00522) antibody
Application Info Presenilin1 antibody can be used for detection of presenilin1 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
Target Reference Sherrington R, Rogaev EI, Liang Y, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer’s disease. Nature1995; 375:754-60.;Weihofen A and Martoglio B. Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides. Trends Cell Biol.2003; 13:71-8.;Periz G and Fortini ME. Functional reconstitution of g-secretase through coordinated expression of presenilin, nicastrin, aph-1, and pen-2. J. Neurosci. Res.2004; 77:309-22.;Selkoe DJ. The cell biology of b-amyloid precursor protein and presenilin in Alzheimer’s disease. Trends Cell Biol.1998; 8:447-53.
Gene Symbol PSEN1
Official Gene Full Name Presenilin-1
NCBI Gene Id 5663
Protein Name Presenilin-1
Description of Target a gamma-secretase subunit
Swissprot Id P49768
Protein Accession # NP_000012.1; NP_015557.2; XP_005267921.1; XP_005267923.1
Nucleotide Accession # NM_000021.3; NM_007318.2; XM_005267864.1; XM_005267866.1
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express PSEN1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express PSEN1.
  1. What is the species homology for "PSEN1 Antibody (OAPB00522)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "PSEN1 Antibody (OAPB00522)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "PSEN1 Antibody (OAPB00522)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PSEN1 Antibody (OAPB00522)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "PSEN1 Antibody (OAPB00522)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PSEN1 Antibody (OAPB00522)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PSEN1 Antibody (OAPB00522)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PSEN1 Antibody (OAPB00522)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "PSEN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PSEN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PSEN1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PSEN1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PSEN1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PSEN1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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