Catalog No: ARP56750_P050
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ARP56750_P050
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Datasheets/ManualsPrintable datasheet for anti-PRR5 (ARP56750_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human PRR5
PurificationAffinity purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 91%; Horse: 86%; Human: 100%; Pig: 100%
Peptide SequenceSynthetic peptide located within the following region: SPAPHSGPCPSRLYPTTQPPEQGLDPTRSSLPRSSPENLVDQILESVDSD
Concentration0.5 mg/ml
Blocking PeptideFor anti-PRR5 (ARP56750_P050) antibody is Catalog # AAP56750
ReferenceGuo,D., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1308-1318
Gene SymbolPRR5
Gene Full Nameproline rich 5
Alias SymbolsPP610, PROTOR1, PROTOR-1, FLJ20185k
NCBI Gene Id55615
Protein Nameproline-rich protein 5
Description of TargetThis gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Uniprot IDP85299-4
Protein Accession #NP_056181
Nucleotide Accession #NM_001017528.2
Protein Size (# AA)293
Molecular Weight32 kDa
Protein InteractionsMTOR; BRCA1; UBC; RICTOR; MAPKAP1; MLST8;
  1. What is the species homology for "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    This item is available "Domestic: within 24 hours delivery | International: 3-5 days".

  3. What buffer format is "PRR5 Antibody - C-terminal region (ARP56750_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    This target may also be called "PP610, PROTOR1, PROTOR-1, FLJ20185k" in publications.

  5. What is the shipping cost for "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "32 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PRR5 Antibody - C-terminal region (ARP56750_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PRR5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PRR5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PRR5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PRR5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PRR5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PRR5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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