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Catalog No: ARP43158_T100
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ARP43158_T100
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-PRPF19 (ARP43158_T100) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human PRPF19
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: PSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVK
Concentration1.0 mg/ml
Blocking PeptideFor anti-PRPF19 (ARP43158_T100) antibody is Catalog # AAP43158 (Previous Catalog # AAPP25128)
ReferenceVoglauer,R., (2006) Exp. Cell Res. 312 (6), 746-759
Publications

Song, G., Cui, Y., Zhong, N. & Han, J. Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium. J. Clin. Pathol. 62, 802-7 (2009). 19403515

Gene SymbolPRPF19
Gene Full NamePRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
Alias SymbolsPSO4, SNEV, PRP19, UBOX4, hPSO4, NMP200
NCBI Gene Id27339
Protein NamePre-mRNA-processing factor 19
Description of TargetPRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM].
Uniprot IDQ9UMS4
Protein Accession #NP_055317
Nucleotide Accession #NM_014502
Protein Size (# AA)504
Molecular Weight55kDa
Protein InteractionsHUWE1; USP4; UBE2D3; SUMO2; CEP76; CEP250; TUBGCP3; CEP57; VCP; UBC; SUMO1; NEDD8; LIN28A; EXOC7; EXOC3; RPA3; RPA2; RPA1; RNF2; SUZ12; EED; rev; MEPCE; SEC13; PARK2; TARDBP; UBD; CSNK2A2; UCHL5; WHSC1; U2AF1; PRCC; HSP90AA1; HSPB1; FN1; RBM10; vif; CDC40
  1. What is the species homology for "PRPF19 Antibody - middle region (ARP43158_T100)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "PRPF19 Antibody - middle region (ARP43158_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PRPF19 Antibody - middle region (ARP43158_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PRPF19 Antibody - middle region (ARP43158_T100)"?

    This target may also be called "PSO4, SNEV, PRP19, UBOX4, hPSO4, NMP200" in publications.

  5. What is the shipping cost for "PRPF19 Antibody - middle region (ARP43158_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PRPF19 Antibody - middle region (ARP43158_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PRPF19 Antibody - middle region (ARP43158_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "55kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PRPF19 Antibody - middle region (ARP43158_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PRPF19"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PRPF19"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PRPF19"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PRPF19"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PRPF19"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PRPF19"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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