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proNT3 Protein (OOPA00031)

Catalog#: OOPA00031
Domestic: within 1 week delivery | International: 1 week
This product is Genway GWB-BSP062
More Information
Product FormatSterile Filtered White lyophilized (freeze-dried) powder.
HostEscherichia Coli.
Additional InformationSolubility: It is recommended to Reconstitution: Reconstitute the lyophilized proNT3 in sterile 18M?-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
::Product Introduction: proNT-3 (the precursor form of neurotrophin-3) functions through p75NTR and sortilin and induces neuronal apoptosis. In contrast, mature NT-3 interacts with Trk receptors and selectively promotes the survival, growth and differentiation of neurons. Since axon retrograde transport is crucial for neurotrophin signaling, proNT-3 also has an important role in the mechanism of retrograde signaling.
Product Description: proNT3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 239 amino acids and having a molecular mass of 27.4kDa. The proNT3 is purified by proprietary chromatographic techniques.
Reconstitution and StorageLyophilized proNT3 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution proNT3 should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.
FormulationproNT3 was lyophilized from a concentrated (1mg/ml) solution in 20mM PB, pH 8.0 and 300mM NaCl.
PurificationGreater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
PurityGreater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Peptide SequenceThe sequence of the first five N-terminal amino acids was determined and was found to be Asn-Asn-Met-Asp-Gln.
Datasheets/ManualsPrintable datasheet for OOPA00031
Gene SymbolproNT3
Alias SymbolsPrecursor Form Neurotrophin-3, proNT-3.
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