PROM1 Recombinant Protein (OPCD06424)

Catalog No: OPCD06424

PROM1 Recombinant Protein (OPCD06424) using SDS-PAGE

PROM1 Recombinant Protein (OPCD06424) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ile171-Asp431
  Subcellular Location: Cell projection, cilium, photoreceptor outer segment. Apical cell membrane; Multi-pass membrane prote
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: PROM1
• Gene Full Name: prominin 1
• Alias Symbols: AC133;antigen AC133;CD133;CORD12;hematopoietic stem cell antigen;hProminin;MCDR2;MSTP061;prominin-1;prominin-like protein 1;PROML1;RP41;STGD4.
• NCBI Gene Id: 8842
• Protein Name: Prominin-1
• Description of Target: May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
• Uniprot ID: O43490
• Protein Accession #: NP_001139319.1
• Nucleotide Accession #: NM_001145847.1
• Protein Size (# AA): Ile171~Asp431
• Molecular Weight: 28kDa