PRLR Antibody - middle region (ARP44370_P050)

Catalog No: ARP44370_P050

Host: Rabbit
Target Name: PRLR
Sample Type: Lymph Node Tumor lysates
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRLR
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: WAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQDFPP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PRLR (ARP44370_P050) antibody is Catalog # AAP44370

Target Info

• Gene Symbol: PRLR
• Gene Full Name: prolactin receptor
• Alias Symbols: HPRL, MFAB, hPRLrI, RI-PRLR
• NCBI Gene Id: 5618
• Protein Name: Prolactin receptor
• Description of Target: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
• Uniprot ID: P16471
• Protein Size (# AA): 622
• Molecular Weight: 68kDa
• Protein Interactions: UBC; BTRC; STAT5B; PRLR; JAK2; CREBBP; FBXW11; CSH1; PRL; YWHAG; SOCS2; SOCS3; NEK3; CISH; YWHAZ; GHR; TEC; VAV2; ZAP70; PTPN11; VAV1; GH1; PPIA; GTF3A;