PRF1 Antibody - HRP Conjugated (OACA00764)

Catalog No: OACA00764

Size:100ug

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: HRP
• Application: Enzyme-linked immunosorbent assay
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Perforin-1 protein (22-554AA)
• Purification: Protein G Purified
• Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
• Reference: [1] Structure and function of human perforin.'Lichtenheld M.G., Olsen K.J., Lu P., Lowrey D.M., Hameed A., Hengartner H., Podack E.R.Nature 335:448-451(1988)
  [2] Molecular cloning and chromosomal assignment of a human perforin (PFP) gene.'Shinkai Y., Yoshida C.M., Maeda K., Kobata T., Maruyama K., Yodoi J., Yagita H., Okumura K.Immunogenetics 30:452-457(1989)
  [3] Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences.'Lichtenheld M.G., Podack E.R.J. Immunol. 143:4267-4274(1989)
• Storage Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Target Info

• Gene Symbol: PRF1
• Gene Full Name: perforin 1
• Alias Symbols: cytolysin;HPLH2;lymphocyte pore-forming protein;P1;perforin 1 (pore forming protein);perforin-1;PFP.
• NCBI Gene Id: 5551
• Protein Name: Perforin-1
• Description of Target: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
• Uniprot ID: P14222