Presenilin-1 N-terminal Peptide (OEMA00013)

Catalog#: OEMA00013
Domestic: within 1-2 weeks delivery International: 1-2 weeks

Size:	1 mg
Price:	$399.00
Availability: In Stock
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Gene Symbol:: PSEN1
NCBI Gene Id:: 5663
Swissprot Id:: P49768
Protein Accession #:: NP_000012.1
Product Format:: Purified, Lyophilized.
Reconstitute in sterile distilled water.
Tissue Tool:: Find tissues and cell lines supported by DNA array analysis to express PSEN1.
RNA Seq:: Find tissues and cell lines supported by RNA-seq analysis to express PSEN1.

Reconstitution and Storage:: Short-term (up to one month) store at 2 to 8C. Long term, store at -20C.
Datasheets/Manuals:: Printable datasheet for OEMA00013

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Protein interactions

Name	# of Products
APBA1	34
APH1A	18
APH1B	13
APP	257
BACE1	58
BCL2	187
C	150
CASP1	98
CASP4	79
CASP8	242
CDH1	128
CDK5	127
CIB1	63
CTNNA1	43
CTNNB1	442
CTNND2	62
DLL1	41
DOCK3	19
ERN1	60
FBXW7	111
FLNB	46
GFAP	32
GSK3B	566
HERPUD1	75
ICAM5	46
JUP	91
KCNIP3	42
MAPT	120
METTL2A	15
MTCH1	8
NCSTN	28
NOTCH4	28
PIK3R1	517
PKP4	33
PSEN1	96
PSENEN	16
RAB11A	42
SCAF11	29
TCF7L2	36
UBQLN1	129
YME1L1	8

Biological pathways

Name	# of Products
amyloid precursor protein catabolic process	16
anti-apoptosis	727
beta-amyloid metabolic process	17
cell-cell adhesion	226
induction of apoptosis by extracellular signals	243
membrane protein ectodomain proteolysis	34
membrane protein intracellular domain proteolysis	40
nerve growth factor receptor signaling pathway	602
Notch receptor processing	32
Notch signaling pathway	129
protein processing	30
smooth endoplasmic reticulum calcium ion homeostasis	8

Biological process

Name	# of Products
activation of MAPKK activity	45
amyloid precursor protein catabolic process	10
anagen	12
anti-apoptosis	239
apoptotic process	586
autophagic vacuole assembly	19
autophagy	48
beta-amyloid metabolic process	9
blood vessel development	69
brain morphogenesis	12
Cajal-Retzius cell differentiation	1
calcium ion transmembrane transport	36
calcium ion transport	94
cell death	133
cell fate specification	23
cell-cell adhesion	77
cerebral cortex cell migration	6
choline transport	3
dorsal/ventral neural tube patterning	19
embryo development	133
embryonic limb morphogenesis	55
endoplasmic reticulum calcium ion homeostasis	4
epithelial cell proliferation	9
forebrain development	60
heart development	186
heart looping	46
hemopoietic progenitor cell differentiation	18
induction of apoptosis by extracellular signals	104
intracellular signal transduction	200
L-glutamate transport	7
locomotion	9
membrane protein ectodomain proteolysis	23
membrane protein intracellular domain proteolysis	12
memory	55
mitochondrial transport	9
myeloid leukocyte differentiation	8
negative regulation of axonogenesis	16
negative regulation of epidermal growth factor-activated receptor activity	10
negative regulation of neuron apoptosis	96
negative regulation of protein kinase activity	53
negative regulation of protein phosphorylation	40
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	6
negative regulation of transcription from RNA polymerase II promoter	574
negative regulation of ubiquitin-protein ligase activity	8
nerve growth factor receptor signaling pathway	173
neurogenesis	29
neuron development	43
neuron migration	89
Notch receptor processing	18
Notch signaling pathway	95
positive regulation of apoptotic process	239
positive regulation of catalytic activity	55
positive regulation of coagulation	5
positive regulation of MAP kinase activity	56
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	40
positive regulation of protein kinase activity	36
positive regulation of protein phosphorylation	125
positive regulation of receptor recycling	11
post-embryonic development	74
protein glycosylation	56
protein processing	40
protein transport	326
proteolysis	456
regulation of phosphorylation	32
regulation of protein binding	14
regulation of resting membrane potential	3
regulation of synaptic plasticity	28
regulation of synaptic transmission, glutamatergic	9
response to DNA damage stimulus	144
response to oxidative stress	104
skeletal system morphogenesis	30
skin morphogenesis	15
smooth endoplasmic reticulum calcium ion homeostasis	5
somitogenesis	47
synaptic vesicle targeting	2
T cell activation involved in immune response	6
T cell receptor signaling pathway	90
thymus development	41

Cellular components

Name	# of Products
apical plasma membrane	173
axon	179
cell cortex	99
cell surface	369
centrosome	253
ciliary rootlet	10
cytoplasmic vesicle	253
dendritic shaft	27
endoplasmic reticulum	837
endoplasmic reticulum membrane	498
gamma-secretase complex	1
Golgi apparatus	794
Golgi membrane	308
growth cone	66
integral to	1
Z disc	54

Protein function

Name	# of Products
aspartic-type endopeptidase activity	81
beta-catenin binding	138
cadherin binding	54
calcium channel activity	94
endopeptidase activity	113
PDZ domain binding	165
peptidase activity	1080
protein binding	12191