PRDX3 Antibody - middle region (OASG06088)

Catalog No: OASG06088

Size:100 uL

Western Blot using HeLa

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human PRX III.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; Immunocytochemistry 1:200-1:1000; ELISA 1:40000;

Target Info

• Gene Symbol: PRDX3
• Gene Full Name: peroxiredoxin 3
• Alias Symbols: AOP1, MER5, AOP-1, SP-22, HBC189, PRO1748, prx-III
• NCBI Gene Id: 10935; 11757; 64371
• Description of Target: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
• Uniprot ID: P30048, P20108, Q9Z0V6
• Molecular Weight: 26 kDa