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Datasheets/Manuals | Printable datasheet for PRDM16 Antibody (OAPB01020) (OAPB01020) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid. PRDM16 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16. The immunogen is located within amino acids 1120 - 1170 of PRDM16. |
Purification | Affinity Purified |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-PRDM16 antibody is Catalog # OEPB03135 |
Application Info | PRDM16 antibody can be used for detection of PRDM16 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 ug/mL. |
Reference | Mochizuki N, Shimizu S, Nagasawa T, et al. A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells. Blood2000; 96:3209-14.;Morishita K. Leukemogenesis of the EVI1/MEL1 gene family. Int. J. Hematol.2007; 85:279-86.;Warner DR, Horn KH, Mudd L, et al. PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue. Biochim. Biophys. Acta2007; 1773:814-20.;Seale P, Bjork B, Yang W, et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature2008; 454:961-7. |
Gene Symbol | PRDM16 |
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Gene Full Name | PR/SET domain 16 |
Alias Symbols | CMD1LL;histone-lysine N-methyltransferase PRDM16;KMT8F;LVNC8;MDS1/EVI1-like gene 1;MEL1;PFM13;PR domain 16;PR domain containing 16;PR domain zinc finger protein 16;PR domain-containing protein 16;transcription factor MEL1. |
NCBI Gene Id | 63976 |
Protein Name | PR domain containing 16 [Homo sapiens]|PR domain zinc finger protein 16 |
Description of Target | Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation. |
Uniprot ID | Q9HAZ2 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/CAH71530 |
Molecular Weight | Predicted: 109, 120, 140 kDa Observed: 140 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PRDM16 Antibody (OAPB01020)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "PRDM16 Antibody (OAPB01020)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "PRDM16 Antibody (OAPB01020)" provided in?
This item is provided in "Liquid. PRDM16 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PRDM16 Antibody (OAPB01020)"?
This target may also be called "CMD1LL;histone-lysine N-methyltransferase PRDM16;KMT8F;LVNC8;MDS1/EVI1-like gene 1;MEL1;PFM13;PR domain 16;PR domain containing 16;PR domain zinc finger protein 16;PR domain-containing protein 16;transcription factor MEL1." in publications.
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What is the shipping cost for "PRDM16 Antibody (OAPB01020)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PRDM16 Antibody (OAPB01020)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PRDM16 Antibody (OAPB01020)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 109, 120, 140 kDa Observed: 140 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PRDM16 Antibody (OAPB01020)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PRDM16"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PRDM16"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PRDM16"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PRDM16"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PRDM16"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PRDM16"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.