Catalog No: OPCD06368
Price: $0.00
SKU
OPCD06368
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Datasheets/Manuals | Printable datasheet for PRDM1 Recombinant Protein (OPCD06368) |
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Predicted Species Reactivity | Mouse|Mus musculus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Asn576-Val813 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | Prdm1 |
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Gene Full Name | PR domain containing 1, with ZNF domain |
Alias Symbols | B lymphocyte induced maturation protein;B lymphocyte-induced maturation protein 1;b2b1765C;b2b1765Clo;beta-interferon gene positive regulatory domain I-binding factor;Bli;Blim;Blimp1;Blimp-1;PR domain zinc finger protein 1;PR domain-containing protein 1;PRDI-;PRDI-BF1;ZNFPR1A1. |
NCBI Gene Id | 12142 |
Protein Name | PR domain zinc finger protein 1 |
Description of Target | Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs (PubMed:27102484). Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (PubMed:27102484). Binds specifically to the PRDI element in the promoter of the beta-interferon gene (By similarity). Drives the maturation of B-lymphocytes into Ig secreting cells (By similarity). Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (PubMed:27102484). |
Uniprot ID | Q60636 |
Protein Accession # | NP_031574.2 |
Nucleotide Accession # | NM_007548.4 |
Protein Size (# AA) | Asn576~Val813 |
Molecular Weight | 34kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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