Catalog No: OPCD06363
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OPCD06363
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Datasheets/ManualsPrintable datasheet for PRAME Recombinant Protein (OPCD06363)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Asn416-Leu502
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPRAME
Gene Full NamePRAME nuclear receptor transcriptional regulator
Alias Symbolscancer/testis antigen 130;CT130;MAPE;melanoma antigen preferentially expressed in tumors;OIP4;OIP-4;opa-interacting protein 4;Opa-interacting protein OIP4;preferentially expressed antigen in melanoma;preferentially expressed antigen of melanoma.
NCBI Gene Id23532
Protein NameMelanoma antigen preferentially expressed in tumors
Description of TargetFunctions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
Uniprot IDP78395
Protein Accession #NP_001278644.1
Nucleotide Accession #NM_001291715.1
Protein Size (# AA)Asn416~Leu502
Molecular Weight14/16kDa
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