PPP6R1 Antibody - N-terminal region (ARP55109_P050)

Catalog No: ARP55109_P050

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WB Suggested Anti-PPP6R1 Antibody Titration: 0.2-1 ug/ml
Positive Control: RPMI 8226 cell lysatePPP6R1 is supported by BioGPS gene expression data to be expressed in RPMI 8226

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PPP6R1 (ARP55109_P050) antibody is Catalog # AAP55109 (Previous Catalog # AAPP41302)
• Sample Type Confirmation:

  PPP6R1 is supported by BioGPS gene expression data to be expressed in RPMI 8226

Target Info

• Gene Symbol: PPP6R1
• Gene Full Name: Protein phosphatase 6, regulatory subunit 1
• Alias Symbols: PP6R1, SAPS1, SAP190, KIAA1115
• NCBI Gene Id: 22870
• Protein Name: Serine/threonine-protein phosphatase 6 regulatory subunit 1
• Description of Target: Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]).
• Uniprot ID: Q9UPN7
• Protein Accession #: NP_055746
• Nucleotide Accession #: NM_014931
• Protein Size (# AA): 881
• Molecular Weight: 97kDa
• Protein Interactions: UBC; AGO1; ANKRD52; MOB1B; ANKRD44; ACAD11; SRPRB; PPP6R3; MOB1A; CNOT10; ANKRD28; CNOT1; ILVBL; PFDN6; C2CD5; KNTC1; PPP6R2; GTF3C4; ARHGEF2; USP10; SGPL1; IKBKAP; TTF2; SRPR; PPP6C; PFDN5; PFDN2; PDCD2; HSPA4; HADHB; HADHA; ACSL3; ALDH3A2; EGFR; HDAC11;