PPP2R1B Antibody - C-terminal region (OASG06021)

Catalog No: OASG06021

Size:100 uL

Western Blot using HeLa

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the C-terminal region of human PP2A-ABeta. Location: 530-610aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: PP2A-ABeta Polyclonal Antibody detects endogenous levels of PP2A-ABeta protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; Immunocytochemistry 1:200-1:1000; ELISA 1:40000;

Target Info

• Gene Symbol: PPP2R1B
• Gene Full Name: protein phosphatase 2, regulatory subunit A, beta
• Alias Symbols: PR65B, PP2A-Abeta
• NCBI Gene Id: 5519; 73699; 315648
• Description of Target: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
• Uniprot ID: P30154, Q7TNP2, Q4QQT4
• Molecular Weight: 66 kDa